Rapid DNA mapping by fluorescent single molecule detection
نویسندگان
چکیده
منابع مشابه
Rapid DNA mapping by fluorescent single molecule detection
DNA mapping is an important analytical tool in genomic sequencing, medical diagnostics and pathogen identification. Here we report an optical DNA mapping strategy based on direct imaging of individual DNA molecules and localization of multiple sequence motifs on the molecules. Individual genomic DNA molecules were labeled with fluorescent dyes at specific sequence motifs by the action of nickin...
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ژورنال
عنوان ژورنال: Nucleic Acids Research
سال: 2006
ISSN: 1362-4962,0305-1048
DOI: 10.1093/nar/gkl1044